Congenital Toxoplasmosis
Toxoplasmosis: Literature and links Toxoplasmosis: Frequently Asked Questiones Toxoplasmosis: Prevention We are here !! Toxoplasmosis: Diagnosis Toxoplasmosis: Symptoms Toxoplasmosis: Ways of infection Toxoplasmosis: Main-page Congenital Toxoplasmosis

Treatment

MIND: There exist many different treatment-schemes. 
      No warranty 
      Check indications, contraindications and side effects

Any maternal infection should be treated with antibiotic drugs until delivery, a fetal infection too.
The newborn baby (after diagnosis of a fetal infection or diagnosed at/after birth) should be treated, too!

Treatment of pregnant women

Before 16th weeks' gestation

4 weeks Spiramycine [Rovamycine©]

After 16th weeks' gestation

until You get the result of fetal diagnostics, or if
fetus is infected, or if
no fetal diagnostic available and a high risk for fetal infection [= Seroconversion, or persistend IgM in the 2nd or 3rd Trimenon]:

alternating to birth
4 weeks combination of:Pyrimethamin [Daraprim©], Sulfadiazin, Folinic Acid
4 weeks Spiramycine [Rovamycine©]

After 16th weeks' gestation, if fetus is not infected:

Spiramycine [Rovamycine©] to birth

The combination of:Pyrimethamin [Daraprim©], Sulfadiazin, can pass through placenta and treat the fetus. But it is not allowed to give before about 16th weeks' gestation.

Treatment of prenataly infected children

Treatment of prenataly infected children with overt (symptomatic) disease

6 months: Combination of:
Pyrimethamin [Daraprim©)
Sulfadiazin
Folinic Acid
6 months: alternating to the first birthday
4 weeks Spiramycine [Rovamycine©]
4 weeks Pyrimethamin [Daraprim©], Sulfadiazin, Folinic Acid
In case of signs of acute inflammation:
Corticosteroids (Prednisolon)

Treatment of prenataly infected children with subclinical infection (no symptoms)

6 weeks: A Combination of:
Pyrimethamin [Daraprim©]
Sulfadiazin
Folinic Acid
6 weeks: B
Spiramycine [Rovamycine©]
alternating A and B to the first birthday
4 weeks Pyrimethamin [Daraprim©], Sulfadiazin, Folinic Acid
6 weeks Spiramycine [Rovamycine©]

 

Congenital Toxoplasmosis
Toxoplasmosis: Literature and links Toxoplasmosis: Frequently Asked Questiones Toxoplasmosis: Prevention Here Toxoplasmosis: Diagnosis Toxoplasmosis: Symptoms Toxoplasmosis: Ways of infection Toxoplasmosis: Main-page Congenital Toxoplasmosis

This page was established by: Alex Trojovsky


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file last changed: August 20th, 2000.